Leslie Tyrone graduated Princeton University with an A.B. in Architecture, and Columbia University with a Masters in Architecture. While in school she worked at a post production house as an intern, which began a trajectory of learning that encompassed many 3d modeling and animation technologies, including software such as Maya, SoftImage, Alias, and 3DStudio Max. This interest in computer aided design led to a professional focus in CAD driven manufacturing processes, which informs much of the studio's work today.

She traveled to Berlin for two months on a Getty Travel Grant to study Mies van der Rohe's European work in conjunction with a show at the MoMA by Terry Riley and Barry Bergdoll entitled "Mies in Berlin". The Grant grew out of a PhD joint seminar conducted through Columbia and the MoMA on Mies van der Rohe. She was Columbia University's Ware Slide Library Curator for two years while in school. After finishing school she worked for Skidmore Owings & Merrill in the transportation group, then returned home to Atlanta to work for Perkins + Will in the education group. She then spent a year working on public art and art gallery projects for Amy Landesberg Architects.

In early 2005 Leslie founded LEFT ARC (the name comes from her initials), a multidisciplinary firm focusing on residential and small commercial architecture and design. In April 2007 Leslie participated in the ATL: MODERN events; please see www.atlmodern.com and www.modern-atlanta.com for more details. She taught a graduate level architecture studio at Georgia Tech as well as a studio course entitled "The Theory of Interior Design" at the Ernest G. Welsch School of Art and Design at Georgia State in the fall of 2007.

Current projects include an off-the-grid green vacation home outside of Breckenridge, Colorado, a mid-century modern home restoration in Atlanta, a custom home in South Carolina, and a restaurant in Atlanta.